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New Delhi: People who have received two doses of a vaccine against Covid are at risk of becoming infected and spreading the delta variant, especially in home settings, according to the results of a trial published on Thursday. lancet infectious disease Publication.
However, the risk is still low compared to those who have not been vaccinated, concluded the study by researchers from Imperial College London in the UK. People who were vaccinated were also found to clear the infection more quickly.
However, the peak viral load among vaccinated people is similar to that seen in unvaccinated people, which may explain why they can still easily pass the virus on in home settings.
“Vaccines are critical to controlling the pandemic, as we know they are very effective in preventing serious illness and deaths from Covid-19,” Ajit Lalwani of Imperial College London in the UK said in a statement. .
“However, our findings suggest that vaccination alone is not sufficient to prevent people from becoming infected with the delta variant and spreading it in home settings,” Lalwani said.
“The ongoing transmission we are seeing among vaccinated people makes it essential for non-vaccinated people to vaccinate themselves to protect themselves from infection and severe Covid-19, especially more people in the winter months. will spend time in close proximity during the period,” he added.
the study
The study enrolled 621 participants identified by the UK contact tracing system between September 2020 and September 2021. All the participants had mild Covid disease or were asymptomatic.
The researchers were able to measure changes in the amount of virus in a person’s nose and throat by performing PCR tests on swab samples provided by each participant daily for 14-20 days.
A total of 205 household contacts of the Delta variant index cases were identified, of whom 53 tested positive for Covid. Of the 205 contacts, 62 percent received two vaccine doses, 19 percent received one vaccine dose, and 19 percent were not vaccinated.
Of the household contacts who had received two doses of the vaccine, 25 percent became infected with the delta variant, compared with 38 percent of non-vaccinated household contacts.
In vaccinated contacts infected with the delta variant, the length of time since vaccination was 101 days, compared with 64 days for uninfected contacts. This suggests an increased risk of infection within three months of receiving the second dose of the vaccine – possibly due to a decrease in protective immunity.
Viral loads declined more rapidly among people infected with the delta variant than among non-vaccinated people with delta, alpha, or pre-alpha.
However, the researchers note that vaccinated people did not record a lower peak viral load than non-vaccinated people, which may explain why the delta variant can still spread despite vaccination because of the peak viral load phase. People are most contagious during
“Understanding the extent to which vaccinated people can transmit the delta variant to others is a public health priority. By repeatedly and repeatedly sampling contacts of COVID-19 cases, we found that vaccinated people can become infected and pass on the infection within households, including to vaccinated household members are involved,” said study co-lead author Anika Singanayagam. Statement.
(Edited by Paramita Ghosh)
Read also: India receives at least 17 samples of Covid type AY.4.2, leading to thousands of cases in UK
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