Washington: A recent study led by a team of clinical researchers found that women who got their first period (menarche) at an early age were more likely to report chronic pain in adulthood. The findings of the study were published in the journal ‘PAIN’, the official publication of the International Association for the Study of Pain (IASP).
According to new research by Charlotte Indre Lund, PhD Fellow in Epidemiology at Oslo University Hospital, and her colleagues, “We found strong links between age at menarche and the outcomes of chronic pain in adult women.”
The findings add to previous evidence that increased estrogen levels associated with early menarche may contribute to pain, and gender differences in pain in general. The study included data on more than 12,000 women (median age 55) who participated in the Troms Study. Ongoing population study of people’s health in northern Norway.
Researchers analyzed the relationship between women’s self-reported age at menarche and the presence and characteristics of chronic pain. The average age of women at menarche was about 13 years. About 40 percent of women experienced chronic pain. Younger women at the time of menarche are more likely to develop chronic pain.
After adjusting for potential confounding factors, there was a 2 percent reduction in the relative risk of chronic pain for each one year delay in menarche. The absolute risk decreased from 1.1 to 1.4 percentage points per year. The absolute risk of chronic pain varied by 12.6 percentage points across the full range of reported ages — from 9 to 18 years old.
Older age at menarche was evaluated in each of the 10 body regions with lower rates of chronic pain, with the strongest associations for chest and abdominal pain. Younger age at menarche was associated with longer duration of pain. Based on the recently updated criteria, the prevalence of chronic widespread pain (CWP) was 7.4 percent.
Later menarche was associated with a lower risk of experiencing CWP, with a risk ratio of 7 percent and an absolute risk difference of 1.5 percentage points per year. Based on the new findings, the researchers concluded that “age at menarche is an independent risk. Factors for chronic pain, site-specific chronic pain, and chronic widespread pain and (thereby) contribute to the explanation of gender differences in pain.” Huh.”
Each additional year of delayed first menstruation is associated with a lower risk of chronic pain lasting 5 years or more, as well as a lower risk of CWP.
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