India, US scientists discover protein in human body responsible for liver cancer

A protein named beta-2 spectrin (SPTBN1) has been discovered in the human body by a group of scientists from Jamia University’s Center for Interdisciplinary Research in Basic Sciences and George Washington University in the United States.

The progression of liver cancer or disease is due to this protein. Scientists believe that their research will help in effective management of liver diseases.

what experts say

Dr. Lopa Mishra, an eminent gastroenterologist and director of the Center for Translational Medicine at George Washington University, and Dr. Imtiaz Hasan of Jamia Millia University and his research fellow Taj Mohammed, investigated the role of beta-2 spectrin protein.

Protein promotes liver disease and lump formation:

Scientists from both universities found that the protein was responsible for the development of liver cancer in mice during this study. They also identified that reducing the effects of this protein in mice could prevent obesity, fibrosis, fat accumulation and liver tissue damage.

This study has shown that effective use of drugs can prevent the progression of liver diseases by reducing the effect of beta-2 spectrin protein.

What causes liver cancer?

According to Dr Prateek Tibdeval, a gastroenterologist at Wockhardt Hospital, Mumbai, liver cancer can occur in any organ.

He also points out that hepatitis B virus (HBV) or hepatitis C virus (HCV) infection results in the accumulation of fat in the liver.

In addition, excessive alcohol consumption can also lead to liver dysfunction, which can eventually lead to cancer. Dr Tibdeval says that liver disease can happen to anyone, not just alcoholics. It can also be due to any type of fat accumulation in the liver.

The liver is the largest organ in the body, roughly the size of a football. It is located on the right side of your abdomen, just below your rib cage. It is responsible for digesting food and eliminating toxins from the body.

The results of this study were published in the journal “Science Translational Medicine,” which is published by the American Association for the Advancement of Science.

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