Long-term impact of COVID-19: Japanese man diagnosed with anal fissure syndrome

It has been almost two years since COVID-19 made its debut and scientists are still studying the effects of SARS-CoV-2 leaves on various body parts. In the latest case, a 77-year-old Japanese man who recovered from COVID-19 was found to have ‘restless anal syndrome’.

His case report was published in BMC Infectious Diseases. It was found that several weeks after the man was tested free of the virus and discharged from the hospital, he began to experience discomfort, deep anal discomfort, which was about 10 cm away from the perineal region. Exercise such as walking or running provided some relief from symptoms, while rest made them worse. Additionally, symptoms intensified during the evening. The patient also had to take pills to sleep.

After ruling out a wide range of diseases with the help of diagnostic tests, doctors concluded that he is the first person in the world to present anal restless syndrome after COVID-19. It is a type of restless leg syndrome (RLS). It results from dysfunction of the central nervous system causing both sensory and motor symptoms.

This case met the four essential characteristics of restless leg syndrome – urge to move, worsening at rest, improvement with exercise, and worsening in the evening. The journal observed that the report may reflect the concomitant effects of COVID-19 on a patient’s neuropsychiatric status.

Reported neuropsychiatric manifestations of COVID-19 include delirium, confessional states, impaired olfactory and taste sensations, acute psychosis, encephalitis, and acute cerebrovascular events. However, the understanding of neuropsychiatric changes associated with the disease remains in its infancy.

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