Scientists revive cells in dead pigs’ organs – Times of India

The pigs had been dead in the lab for an hour. There was no blood circulating in his body; His heart was still, his brain waves were flat. a group of Yale Scientists pumped a custom-made solution into the bodies of dead pigs with a device similar to a heart-lung machine. What happened next adds to the question of what science considers the wall between life and death.
Although the pigs were by no means conscious, their seemingly dead cells were regenerated. As a solution, his heart started beating, which scientists called OrganEx, circulating in the veins and arteries. The cells in their organs, including the heart, liver, kidneys, and brain, were functioning again, and the animals never hardened like a typical dead pig.
Other pigs that were dead for an hour were treated ECMO, a machine that pumps blood through their body. They became stiff, their limbs were swollen and damaged, their blood vessels collapsed, and they had purple spots on their backs where blood had accumulated. The group reported its results on Wednesday Nature,
Researchers say they aim to one day increase the supply of human organs for transplantation by allowing doctors to obtain viable organs after death. And, he says, he hopes his technique could also be used to prevent serious damage to the heart after a devastating heart attack or to prevent bra ins after a major stroke. But the findings are just a first step, said Stephen Latham, a bioethicist. Yale University who worked closely with the group. He stressed that the technology is “far from being used in humans.”
The work began a few years ago when the group conducted a similar experiment with the brains of dead pigs from a slaughterhouse. Four hours after the pigs died, the group injected a solution similar to OrganEx they called BrainEx and observed that brain cells that should have been dead could be regenerated. This prompted him to ask if he could regenerate a whole body, saying Dr. Zvonimir VerceljaAnother member of the Yale team.
The OrganEx solution contains nutrients, anti-inflammatory drugs, drugs to prevent cell death, nerve blockers S — substances that reduce the activity of neurons and prevent any chances of pigs regaining consciousness — and an artificial hemoglobin each. mixed with the animal’s own blood. Yale has applied for a patent on the technology.
The next step, the scientists said, would be to see if the organs function properly and can be successfully transplanted. Shortly thereafter, the researchers hope to test whether this method can repair damaged hearts or brains.