Georgia: The two most significant risk factors are associated with a relative and a full five-year chance of receiving any cancer According to a recent major study conducted by scientists, older age and smoking are American Cancer Society (ACS).
The research findings were published in the journal Cancer.
The findings also demonstrate that in addition to age and smoking history, physicians should consider excess body obesity, family history of any cancers, and many other factors that may help patients determine whether They may benefit from advanced cancer screening or prevention interventions.
“Single cancer type-specific screening recommendations are based on risk factors for that specific type of cancer,” Dr. alpa patel, senior vice president, population science at the American Cancer Society and lead author of the study. “Our findings are encouraging as we are working to define subgroups in the general population that may benefit from increased cancer screening and prevention.”
For this study, researchers used two ACS prospective cohort studies, the Cancer Prevention Study-II Nutrition Group and the Cancer Prevention Study-3, to identify risk factors associated with a greater than two percent absolute risk of any cancer within five years. analysed. The authors studied 429,991 participants in the United States with no prior personal history of cancer and followed them for five years.
multivariate cox Proportional hazards models were used to estimate hazard ratios (HRs) and 95 percent confidence intervals for association. Using these HRs, individual consistent absolute risk estimate Age was used to calculate absolute risks.
The results showed that 15,226 invasive cancers were diagnosed in the participants within five years of enrollment. The multivariate-adjusted relative risk of any cancer was strongest for current smokers compared to non-smokers. In men, alcohol consumption, family history of cancer, red meat consumption and physical inactivity were also associated with increased risk.
In women, body mass index (BMI), type 2 diabetes, hysterectomy, parity, family history of cancer, high blood pressure, tubal ligation, and physical inactivity were associated with cancer risk.
Almost all individuals over the age of 50 and some individuals under the age of 50, including current or former smokers (less than 30 years since quitting) and long-term nonsmokers with a BMI greater than In the full five years, the risk exceeded two percent. 25 or a first-degree family history of cancer. The full five-year risk was as high as 29 percent in men and 25 percent in women.
Patel said, “As we consider the possibility that future tests may be able to identify many types of cancer, we need to begin to understand which ones are most at risk for developing any type of cancer.” Who is there.” “These types of data are not widely available, but are needed to inform future screening options, such as blood-based multi-cancer early detection tests that could help save lives.”
The research findings were published in the journal Cancer.
The findings also demonstrate that in addition to age and smoking history, physicians should consider excess body obesity, family history of any cancers, and many other factors that may help patients determine whether They may benefit from advanced cancer screening or prevention interventions.
“Single cancer type-specific screening recommendations are based on risk factors for that specific type of cancer,” Dr. alpa patel, senior vice president, population science at the American Cancer Society and lead author of the study. “Our findings are encouraging as we are working to define subgroups in the general population that may benefit from increased cancer screening and prevention.”
For this study, researchers used two ACS prospective cohort studies, the Cancer Prevention Study-II Nutrition Group and the Cancer Prevention Study-3, to identify risk factors associated with a greater than two percent absolute risk of any cancer within five years. analysed. The authors studied 429,991 participants in the United States with no prior personal history of cancer and followed them for five years.
multivariate cox Proportional hazards models were used to estimate hazard ratios (HRs) and 95 percent confidence intervals for association. Using these HRs, individual consistent absolute risk estimate Age was used to calculate absolute risks.
The results showed that 15,226 invasive cancers were diagnosed in the participants within five years of enrollment. The multivariate-adjusted relative risk of any cancer was strongest for current smokers compared to non-smokers. In men, alcohol consumption, family history of cancer, red meat consumption and physical inactivity were also associated with increased risk.
In women, body mass index (BMI), type 2 diabetes, hysterectomy, parity, family history of cancer, high blood pressure, tubal ligation, and physical inactivity were associated with cancer risk.
Almost all individuals over the age of 50 and some individuals under the age of 50, including current or former smokers (less than 30 years since quitting) and long-term nonsmokers with a BMI greater than In the full five years, the risk exceeded two percent. 25 or a first-degree family history of cancer. The full five-year risk was as high as 29 percent in men and 25 percent in women.
Patel said, “As we consider the possibility that future tests may be able to identify many types of cancer, we need to begin to understand which ones are most at risk for developing any type of cancer.” Who is there.” “These types of data are not widely available, but are needed to inform future screening options, such as blood-based multi-cancer early detection tests that could help save lives.”